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        Aconitine

        更新時間:2022-01-28

        簡要描述:

        A lipid-soluble neurotoxin that acts as a sodium channel modulator. Binds with high affinity to the open state of the voltage-sensitive sodium channels at site 2, thereby causing a persistent ……

        型號:廠商性質:代理商瀏覽量:993
        A lipid-soluble neurotoxin that acts as a sodium channel modulator. Binds with high affinity to the open state of the voltage-sensitive sodium channels at site 2, thereby causing a persistent activation of the sodium channels, which become refractory to excitation.


        Product Details

        Alternative Name:(1α,3α,6α,14α,15α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14,15-pentol 8-acetate 14-benzoate

        Formula:C34H47NO11

        MW:645.7

        Source:Isolated from Aconitum karacolium.

        CAS:302-27-2

        MI:14: 118

        RTECS:AR5960000

        Purity:≥98% (HPLC)

        Appearance:White to off-white powder.

        Solubility:Soluble in 100% ethanol (35mg/ml); almost insoluble in water (0.3mg/ml).

        Shipping:Ambient

        Long Term Storage:+4°C

        Handling:Protect from light.

        Regulatory Status:RUO - Research Use Only

        ALX-550-232
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        ALX-550-232


        Product Literature References

        Non-quantal acetylcholine release at mouse neuromuscular junction: effects of elevated quantal release and aconitine: S.P. Yu & W. Van der Kloot; Neurosci. Lett. 117, 111 (1990), Abstract;
        Synthesis and activity of a potent N-methyl-D-aspartic acid agonist, trans-1-aminocyclobutane-1,3-dicarboxylic acid, and related phosphonic and carboxylic acids: M. Muroi, et al.; Neuropharmacology 29, 567 (1990), Abstract;


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