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        nVivoMAb anti-mouse IL-10

        更新時間:2022-01-27

        簡要描述:

        The JES5-2A5 monoclonal antibody reacts with mouse IL-10. IL-10 is a 17-21 kDa cytokine which is primarily produced by monocytes and, to a lesser extent, Th2 cells, mast cells, T regulatory cells, and

        型號:廠商性質:代理商瀏覽量:697

        The JES5-2A5 monoclonal antibody reacts with mouse IL-10. IL-10 is a 17-21 kDa cytokine which is primarily produced by monocytes and, to a lesser extent, Th2 cells, mast cells, T regulatory cells, and certain subsets of activated T and B cells. IL-10 has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-κB activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggest that this cytokine is an essential immunoregulator in the intestinal tract. The JES5-2A5 antibody has been shown to neutralize the bioactivity of natural or recombinant IL-10.


        產品名稱:InVivoMab anti-mouse IL-10

        反應種屬:mouse

        宿主來源:rat

        實驗應用:in vivo IL-10 neutralization, in vitro IL-10 neutralization

        同種型:IgG1, κ

        免疫原:Recombinant mouse IL-10

        克隆性:Monoclonal

        克隆號:JES5-2A5

        產品濃度:Lot specific,typically between 4-11 mg/ml

        保存溫度:Undiluted at 4°C in the dark

        運輸溫度:Ship with adequate amount of blue ice to ensure the product remains at 4°C for the duration of transit

        預期分子量:150 kDa

        產品形式:液體

        有效期:One year from the date of receipt if stored as recommended

        產地:美國


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