StressMarq Ionomycin（離子霉素）（SIH-228）

Ionomycin (SIH-228)的化學(xué)結(jié)構(gòu)圖, Ca2+ 離子載體. CAS #: 56092-81-0. 分子式: C41H70O9. 分子量: 709.01 g/mol.

產(chǎn)品詳情

產(chǎn)品名稱：Ionomycin

產(chǎn)品描述：Ca2+ 離子載體

純度：>98%

CAS號(hào)：56092-81-0

分子式：C41H70O9

分子量：709.01

儲(chǔ)存溫度：-20oC

運(yùn)輸溫度：常溫運(yùn)輸

產(chǎn)品類型：誘導(dǎo)劑

溶解性：在乙醇中溶解度是10mM, DMSO中是10mM

來(lái)源：合成的

性狀：無(wú)色固體

SMILES：C[C@H](CCC(=O)O)C[C@H](C)C[C@H](C)C(=O)/C=C(/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@H]([C@@H](C)[C@H](C[C@@H]1CC[C@@](O1)(C)[C@H]2CC[C@@](O2)(C)[C@@H](C)O)O)O)O

InChI：InChI=1S/C41H72O9/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23

InChIKey：PGHMRUGBZOYCAA-OJFQOPKISA-N

安全術(shù)語(yǔ)：安全級(jí)別: 注意: 物質(zhì)尚未充分測(cè)試. 安全術(shù)語(yǔ): S22 -不要吸入粉塵 S24/25 - 避免皮膚和眼睛接觸 S36/37/39 - 穿戴適當(dāng)?shù)姆雷o(hù)服、手套和眼睛/面部保護(hù) 危險(xiǎn)術(shù)語(yǔ): H302, 吞食有害

引用該產(chǎn)品：Ionomycin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-228)

別名：Ionomycin, Ionomycin calcium salt

研究領(lǐng)域：癌癥, 細(xì)胞凋亡

PubChem ID：6434517

科研背景：Ionomycin is a calcium ionophore used in research to raise the intracellular level of calcium and as a tool to understand calcium transport across biological membranes. It is also used to stimulare the intracellular production of the cytokines interferon, perforin, IL-2 and IL-4. It is more specific than A23187.

參考資料：1. Holmes A.G. Watt M.J., Carey A.L. And Febbraio M.A. (2004) Metabolism. 53(11): 1492-1495.

2. Abramov A.Y., Duchen M.R. (2003) Cell Calcium. 33(2): 101-112.

產(chǎn)品文獻(xiàn)：

Isolation and immunophenotyping by flow cytometry of canine peripheral blood and intraepithelial and lamina propria duodenal T lymphocytes.

Agulla, B. et al. (2021) Vet. Immunol. Immunopathol. . 239:110305

PubMed ID: 34352607 應(yīng)用范圍: In vitro stimulation

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